I am assuming that you have applied for an H1B visa..Here are the answers to your Questions.
1. Could we expedite the 221g response as spouse is suffering in US.
The 221G process can not be expedited, you can write a letter to consulate explaining the hardships you are facing while living away from family.
2. Could I appear for H4 visa ( Spouse is on H1B in US) while H1B is under administrative processing.
Yes. But you have to withdraw the H1B Visa application
3. Could I transfer my H1B with any other employer.
Yes, you can transfer your H1B Visa
4. Any other possible option please.
The best option is to travel on H4, find another project and COS to H1B. If you have a project, it is unlikely that the COS will be denied.
Do you have a valid B1 Visa?
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